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PubMed COVID-19 Clinical Care

5501 - 5510 of 8011 results found

COVID-19 infection in myasthenia gravis: Clinical course and outcomes

Date
Friday, June 16, 2023 - 4:00 AM
Description
INTRODUCTION/AIMS: Myasthenia gravis (MG) patients have been predicted to have high rates of coronavirus disease-2019 (COVID-19) complications due to frequent involvement of respiratory muscles in MG and frequent use of immunosuppressive therapies

COVID infection in 4 steps: Thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive the nature and degree of infection in human COVID-19 disease

Date
Friday, June 16, 2023 - 4:00 AM
Description
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection, exploring the relationship between the viral diffusion in the mucosa and viral affinity for the angiotensin converting enzyme 2 (ACE2) target. Utilising the structural