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PubMed COVID-19 Clinical Care

8471 - 8480 of 63288 results found

Structure determination needs to go viral

Date
Monday, January 29, 2024 - 4:00 AM
Description
Viral diseases are expected to cause new epidemics in the future, therefore, it is essential to assess how viral diversity is represented in terms of deposited protein structures. Here, data were collected from the Protein Data Bank to screen the

On the origins of SARS-CoV-2 main protease inhibitors

Date
Monday, January 29, 2024 - 4:00 AM
Description
In order to address the world-wide health challenge caused by the COVID-19 pandemic, the 3CL protease/SARS-CoV-2 main protease (SARS-CoV-2-M^(pro)) coded by its nsp5 gene became one of the biochemical targets for the design of antiviral drugs. In